{"id":148536,"date":"2023-09-02T07:47:20","date_gmt":"2023-09-02T02:17:20","guid":{"rendered":"https:\/\/dripp.zone\/news\/?p=148536"},"modified":"2023-09-02T07:47:20","modified_gmt":"2023-09-02T02:17:20","slug":"just-one-dose-of-magic-mushroom-psychedelic-can-ease-depression-for-weeks-study-finds-crypto-news","status":"publish","type":"post","link":"https:\/\/dripp.zone\/news\/just-one-dose-of-magic-mushroom-psychedelic-can-ease-depression-for-weeks-study-finds-crypto-news\/","title":{"rendered":"Just One Dose of Magic Mushroom Psychedelic Can Ease Depression for Weeks, Study Finds &#8211; Crypto News"},"content":{"rendered":"<p><\/p>\n<div style=\"position:relative;overflow:visible;font-size:1.2em;line-height:1.58\">\n<p class=\"font-meta-serif-pro scene:font-noto-sans scene:text-base scene:md:text-lg font-normal text-lg md:text-xl md:leading-9 tracking-px text-body gg-dark:text-neutral-100\">The psychedelic ingredient in \u201cmagic mushrooms\u201d continues to reveal therapeutic powers, according to a new study.<\/p>\n<p class=\"font-meta-serif-pro scene:font-noto-sans scene:text-base scene:md:text-lg font-normal text-lg md:text-xl md:leading-9 tracking-px text-body gg-dark:text-neutral-100\">In a significant randomized controlled trial, researchers at 11 sites across the US compared a single dose of psilocybin with a placebo concluding that the chemical could have positive effects on people suffering from depression.<\/p>\n<p class=\"font-meta-serif-pro scene:font-noto-sans scene:text-base scene:md:text-lg font-normal text-lg md:text-xl md:leading-9 tracking-px text-body gg-dark:text-neutral-100\">The study, published in the Journal of the American Medical Association (<a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2808950?guestaccesskey=7ff7bcd4-634a-4faa-ae0f-3ed11e9ef407&amp;utm_source=for_the_media&amp;utm_medium=referral&amp;utm_campaign=ftm_links&amp;utm_content=tfl&amp;utm_term=083123\" class=\"sc-adb616fe-0 ePvUAp\">JAMA<\/a>), indicates that psilocybin (the ingredient that makes you trip when consuming mushrooms with your friends) may offer a faster and more durable solution than existing antidepressants for treating major depressive disorder (MDD), with effects noticeable within a week.<\/p>\n<p class=\"font-meta-serif-pro scene:font-noto-sans scene:text-base scene:md:text-lg font-normal text-lg md:text-xl md:leading-9 tracking-px text-body gg-dark:text-neutral-100\">\u201cPsilocybin treatment was associated with a clinically significant sustained reduction in depressive symptoms and functional disability, without serious adverse events,\u201d the study concludes. \u201cThese findings add to increasing evidence that psilocybin\u2014when administered with psychological support\u2014may hold promise as a novel intervention for MDD.\u201d<\/p>\n<p><span class=\"\" \/><\/p>\n<p class=\"font-meta-serif-pro scene:font-noto-sans scene:text-base scene:md:text-lg font-normal text-lg md:text-xl md:leading-9 tracking-px text-body gg-dark:text-neutral-100\">Magic mushrooms, once a staple of \u201860s counterculture, are <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.nature.com\/articles\/s41598-022-14512-3.epdf?sharing_token=TFqWBNy740_gQSsQPAYnfdRgN0jAjWel9jnR3ZoTv0MBv3IGcUUazdX_pmE0HRKlYBpwUH51MRxY2r4pJertbLgGgjTEhs-YboJmolWwLcQ_L3z6pSDj012vVw_OmrKuyWjf_vhHu5vlKAq_L_wWsZwzr24LGDvhtMPKrMZxMX8%3D\" class=\"sc-adb616fe-0 ePvUAp\">gaining renewed attention<\/a> for their potential therapeutic benefits. The study found that psilocybin treatment was associated with a clinically significant sustained reduction in depressive symptoms. The psychedelic also showed promise in different areas, including reduced overall disease severity and improved quality of life.<\/p>\n<p class=\"font-meta-serif-pro scene:font-noto-sans scene:text-base scene:md:text-lg font-normal text-lg md:text-xl md:leading-9 tracking-px text-body gg-dark:text-neutral-100\">The new trial recruited 104 adults diagnosed with moderate to severe MDD. Participants were randomly assigned to receive either a low dose of synthetic psilocybin or an active placebo, along with psychological support before, during, and after ingesting the capsule.<\/p>\n<figure class=\"w-full max-w-full mt-4 overflow-hidden\"><span style=\"overflow:hidden;width:initial;height:initial;background:none;border:0;margin:0;padding:0;position:relative\"><span style=\"width:initial;height:initial;background:none;border:0;margin:0;padding:0;padding-top:56.45536010620644%\" \/><img decoding=\"async\" alt=\"\" loading=\"lazy\" data-nimg=\"responsive\" style=\"position:absolute;top:0;left:0;bottom:0;right:0;padding:0;border:none;margin:auto;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain\" class=\"absolute inset-0 box-border p-0 border-0 m-auto block w-0 h-0 min-w-full max-w-full min-h-full max-h-full object-contain\" src=\"https:\/\/img.decrypt.co\/insecure\/rs:fit:1536:0:0:0\/plain\/https:\/\/cdn.decrypt.co\/wp-content\/uploads\/2023\/09\/joi230092va_1692829956.77163.png@webp\" \/><\/span><figcaption class=\"m-0 text-left gg-dark:text-neutral-200 scene:font-itc-avant-garde-gothic-pro scene:text-neutral-700 scene:font-light scene:mt-1\">Source: JAMA<\/figcaption><\/figure>\n<p class=\"font-meta-serif-pro scene:font-noto-sans scene:text-base scene:md:text-lg font-normal text-lg md:text-xl md:leading-9 tracking-px text-body gg-dark:text-neutral-100\">In a departure from earlier studies, this trial employed blinded, remote raters to assess patients\u2019 depressive symptoms using the <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.mdcalc.com\/calc\/4058\/montgomery-asberg-depression-rating-scale-madrs\" class=\"sc-adb616fe-0 ePvUAp\">Montgomery-Asberg depression scale<\/a> (a standardized checklist to determine how severe a state of depression is). This approach minimizes the chances that expectations could influence the results.<\/p>\n<p class=\"font-meta-serif-pro scene:font-noto-sans scene:text-base scene:md:text-lg font-normal text-lg md:text-xl md:leading-9 tracking-px text-body gg-dark:text-neutral-100\">So what did they find? Compared with placebo, psilocybin caused a significant reduction in depression scores after just eight days. By the six-week mark, almost half of psilocybin patients showed a sustained antidepressant response, versus only 11% on placebo.<\/p>\n<p class=\"font-meta-serif-pro scene:font-noto-sans scene:text-base scene:md:text-lg font-normal text-lg md:text-xl md:leading-9 tracking-px text-body gg-dark:text-neutral-100\">While standard antidepressants can take four to six weeks to become effective, this study adds to the growing body of evidence suggesting that psychedelic therapy may offer rapid relief from depressive symptoms.<\/p>\n<p class=\"font-meta-serif-pro scene:font-noto-sans scene:text-base scene:md:text-lg font-normal text-lg md:text-xl md:leading-9 tracking-px text-body gg-dark:text-neutral-100\">Although the study is the largest randomized, blinded multicenter trial to date affirming psilocybin\u2019s effectiveness for depression, it&#8217;s important to note that psilocybin was administered in a controlled and monitored setting, not taken recreationally. Experts advise that assisted psychotherapy is crucial for maximizing the therapeutic potential of psilocybin, as emphasized by a <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9751063\/\" class=\"sc-adb616fe-0 ePvUAp\">research paper<\/a> written by doctors from the University of British Columbia.<\/p>\n<h2 class=\"sc-2ed2039d-2 hmmXcn gg-dark:text-white scene:font-itc-avant-garde-gothic-pro scene:font-light\" style=\"margin-top:2em;text-align:left;padding-bottom:16px;margin-bottom:16px;border-bottom:1px solid #dfe2e4\">No magic solution<\/h2>\n<p class=\"font-meta-serif-pro scene:font-noto-sans scene:text-base scene:md:text-lg font-normal text-lg md:text-xl md:leading-9 tracking-px text-body gg-dark:text-neutral-100\">The exact mechanisms by which psilocybin acts quickly against depression remain a subject of <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/edition.cnn.com\/2022\/06\/11\/health\/psilocybin-brain-changes-life-itself-wellness-scn\/index.html\" class=\"sc-adb616fe-0 ePvUAp\">ongoing research<\/a>. Some theories suggest it temporarily alters the connectivity of brain circuits, which are often disorganized in mood disorders. This alteration may allow the brain to break free from negative thought patterns after a single dose.<\/p>\n<p class=\"font-meta-serif-pro scene:font-noto-sans scene:text-base scene:md:text-lg font-normal text-lg md:text-xl md:leading-9 tracking-px text-body gg-dark:text-neutral-100\">\u201cSomething about psychedelic treatment of addiction that is exciting is that the mechanisms we hope it will work are not really specific to any particular addiction,\u201d Dr. Michael Bogenschutz, a psychiatry professor at NYU studying psilocybin <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/time.com\/6167638\/psilocybin-addiction-therapeutic-breakthrough\/\" class=\"sc-adb616fe-0 ePvUAp\">told TIME magazine<\/a>. \u201cIt increases the capacity of the brain to change, and therefore for thinking and behavior to change.\u201d<\/p>\n<p class=\"font-meta-serif-pro scene:font-noto-sans scene:text-base scene:md:text-lg font-normal text-lg md:text-xl md:leading-9 tracking-px text-body gg-dark:text-neutral-100\">Although the study demonstrates psilocybin\u2019s promise, the authors say more research is needed. While generally safe, psychedelics do come with <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/research.dom.edu\/the-war-on-drugs--history-policy-therapeutics\/Side-Effects-of-Psychedelic-Usage\" class=\"sc-adb616fe-0 ePvUAp\">side effects<\/a>, although the study did not specifically list headaches, nausea, panic attacks, and paranoia.<\/p>\n<p class=\"font-meta-serif-pro scene:font-noto-sans scene:text-base scene:md:text-lg font-normal text-lg md:text-xl md:leading-9 tracking-px text-body gg-dark:text-neutral-100\">The study included predominantly white participants and the authors of the study call for more rigorous, longer-term trials with diverse populations. \u201cLarger recent studies have addressed these issues to various degrees, but report primary end points of short duration,14,15 leaving open the question of the long-term clinical utility of psilocybin for an often chronic condition such as MDD,\u201d the researchers said.<\/p>\n<p class=\"font-meta-serif-pro scene:font-noto-sans scene:text-base scene:md:text-lg font-normal text-lg md:text-xl md:leading-9 tracking-px text-body gg-dark:text-neutral-100\">There\u2019s a long road ahead as scientists aim to replicate and extend initial findings. However, the current study marks a major milestone: it provides the clearest indication yet that psychedelic medicine could significantly impact the future of psychiatric treatment.<\/p>\n<div class=\"my-4 border-b border-decryptGridline\">\n<div class=\"text-left p-8 md:py-12 md:px-12 max-w-prose relative\"><span class=\"border-t-4 border-l-4 w-4 h-4 md:border-t-[6px] md:border-l-[6px] md:w-6 md:h-6 border-decryptPurple dark:border-decryptNeon gg-dark:border-cc-pink-2 absolute top-4 left-4 md:top-6 md:left-6\" \/><span class=\"border-t-4 border-l-4 w-4 h-4 md:border-t-[6px] md:border-l-[6px] md:w-6 md:h-6 border-decryptPurple dark:border-decryptNeon gg-dark:border-cc-pink-2 absolute rotate-180 bottom-4 right-4 md:bottom-6 md:right-6\" \/><\/p>\n<h3 class=\"font-akzidenz-grotesk font-bold text-xl md:text-3xl mb-6 md:text-center gg-dark:text-white\">Stay on top of crypto news, get daily updates in your inbox.<\/h3>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>The psychedelic ingredient in \u201cmagic mushrooms\u201d continues to reveal therapeutic powers, according to a new study. In a significant randomized controlled trial, researchers at 11 sites across the US compared a single dose of psilocybin with a placebo concluding that the chemical could have positive effects on people suffering from depression. The study, published in [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":148537,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[230,225,221,227,226,228,229,60,223,224,222],"class_list":["post-148536","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cryptocurrency","tag-brave","tag-coinbase","tag-crypto","tag-decentralised","tag-decentralized","tag-decentralized-exchange","tag-erc-20","tag-featured","tag-meme-coin","tag-robinhood","tag-solana"],"_links":{"self":[{"href":"https:\/\/dripp.zone\/news\/wp-json\/wp\/v2\/posts\/148536","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dripp.zone\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dripp.zone\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dripp.zone\/news\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/dripp.zone\/news\/wp-json\/wp\/v2\/comments?post=148536"}],"version-history":[{"count":2,"href":"https:\/\/dripp.zone\/news\/wp-json\/wp\/v2\/posts\/148536\/revisions"}],"predecessor-version":[{"id":148539,"href":"https:\/\/dripp.zone\/news\/wp-json\/wp\/v2\/posts\/148536\/revisions\/148539"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dripp.zone\/news\/wp-json\/wp\/v2\/media\/148537"}],"wp:attachment":[{"href":"https:\/\/dripp.zone\/news\/wp-json\/wp\/v2\/media?parent=148536"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dripp.zone\/news\/wp-json\/wp\/v2\/categories?post=148536"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dripp.zone\/news\/wp-json\/wp\/v2\/tags?post=148536"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}